| Dataset | RNR_GSEA_DESEQ2_FC |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | DNA_METABOLIC_PROCESS |
| Enrichment Score (ES) | 0.13760506 |
| Normalized Enrichment Score (NES) | 2.522118 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.00422005 |
| FWER p-Value | 0.049 |

| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DMC1 | 813 | 0.614 | -0.0403 | Yes | ||
| 2 | TNP1 | 886 | 0.570 | -0.0403 | Yes | ||
| 3 | PPARGC1A | 1513 | 0.347 | -0.0704 | Yes | ||
| 4 | KRT7 | 1525 | 0.346 | -0.0670 | Yes | ||
| 5 | TOP2A | 1826 | 0.288 | -0.0794 | Yes | ||
| 6 | BTG2 | 1909 | 0.274 | -0.0799 | Yes | ||
| 7 | GADD45G | 2071 | 0.254 | -0.0847 | Yes | ||
| 8 | XPC | 2265 | 0.232 | -0.0912 | Yes | ||
| 9 | RPA1 | 2340 | 0.224 | -0.0913 | Yes | ||
| 10 | ATF7IP | 2439 | 0.214 | -0.0927 | Yes | ||
| 11 | TSPYL2 | 2444 | 0.214 | -0.0890 | Yes | ||
| 12 | ATRX | 2448 | 0.214 | -0.0852 | Yes | ||
| 13 | MSH3 | 2468 | 0.212 | -0.0823 | Yes | ||
| 14 | MLH1 | 2496 | 0.210 | -0.0798 | Yes | ||
| 15 | REV3L | 2653 | 0.197 | -0.0843 | Yes | ||
| 16 | RAG1 | 2709 | 0.193 | -0.0833 | Yes | ||
| 17 | NT5E | 2750 | 0.190 | -0.0816 | Yes | ||
| 18 | RAD51 | 2804 | 0.185 | -0.0805 | Yes | ||
| 19 | RAD21 | 2827 | 0.183 | -0.0777 | Yes | ||
| 20 | ATM | 2839 | 0.183 | -0.0744 | Yes | ||
| 21 | BRCA1 | 2859 | 0.182 | -0.0715 | Yes | ||
| 22 | POLQ | 2918 | 0.178 | -0.0707 | Yes | ||
| 23 | ENPP7 | 2997 | 0.173 | -0.0710 | Yes | ||
| 24 | RAD54L | 3193 | 0.160 | -0.0776 | Yes | ||
| 25 | ORC2 | 3246 | 0.158 | -0.0765 | Yes | ||
| 26 | HMGB2 | 3268 | 0.156 | -0.0737 | Yes | ||
| 27 | RPA4 | 3277 | 0.156 | -0.0702 | Yes | ||
| 28 | ISG20 | 3335 | 0.153 | -0.0693 | Yes | ||
| 29 | CDKN2A | 3352 | 0.153 | -0.0662 | Yes | ||
| 30 | PURA | 3473 | 0.147 | -0.0688 | Yes | ||
| 31 | GADD45A | 3492 | 0.146 | -0.0658 | Yes | ||
| 32 | MCM2 | 3561 | 0.142 | -0.0656 | Yes | ||
| 33 | LIG1 | 3623 | 0.139 | -0.0650 | Yes | ||
| 34 | POLK | 3678 | 0.136 | -0.0639 | Yes | ||
| 35 | RBBP8 | 3743 | 0.133 | -0.0635 | Yes | ||
| 36 | KPNA2 | 3854 | 0.128 | -0.0655 | Yes | ||
| 37 | SETX | 3873 | 0.128 | -0.0625 | Yes | ||
| 38 | ATR | 3902 | 0.127 | -0.0601 | Yes | ||
| 39 | POLA1 | 3973 | 0.124 | -0.0600 | Yes | ||
| 40 | RBMS1 | 3999 | 0.122 | -0.0574 | Yes | ||
| 41 | ATXN3 | 4011 | 0.122 | -0.0540 | Yes | ||
| 42 | TDG | 4118 | 0.118 | -0.0558 | Yes | ||
| 43 | SMC1A | 4150 | 0.117 | -0.0536 | Yes | ||
| 44 | LIG4 | 4313 | 0.111 | -0.0584 | Yes | ||
| 45 | RECQL | 4502 | 0.105 | -0.0647 | Yes | ||
| 46 | TP73 | 4512 | 0.104 | -0.0612 | Yes | ||
| 47 | RFC1 | 4523 | 0.104 | -0.0578 | Yes | ||
| 48 | TERT | 4656 | 0.099 | -0.0611 | Yes | ||
| 49 | SMARCAD1 | 4884 | 0.092 | -0.0695 | Yes | ||
| 50 | ORC3 | 5020 | 0.088 | -0.0729 | Yes | ||
| 51 | ERCC4 | 5043 | 0.088 | -0.0701 | Yes | ||
| 52 | XRCC2 | 5063 | 0.087 | -0.0672 | Yes | ||
| 53 | RAD50 | 5089 | 0.086 | -0.0646 | Yes | ||
| 54 | XRCC5 | 5094 | 0.086 | -0.0609 | Yes | ||
| 55 | RAD54B | 5135 | 0.085 | -0.0591 | Yes | ||
| 56 | BRCA2 | 5211 | 0.083 | -0.0592 | Yes | ||
| 57 | TERF2IP | 5321 | 0.080 | -0.0612 | Yes | ||
| 58 | ERCC6 | 5325 | 0.080 | -0.0574 | Yes | ||
| 59 | EXO1 | 5410 | 0.078 | -0.0580 | Yes | ||
| 60 | UPF1 | 5501 | 0.075 | -0.0590 | Yes | ||
| 61 | CSNK1E | 5539 | 0.074 | -0.0570 | Yes | ||
| 62 | REV1 | 5551 | 0.074 | -0.0537 | Yes | ||
| 63 | MRE11A | 5577 | 0.073 | -0.0511 | Yes | ||
| 64 | KAT7 | 5588 | 0.073 | -0.0477 | Yes | ||
| 65 | LIG3 | 5593 | 0.073 | -0.0439 | Yes | ||
| 66 | MCM3 | 5670 | 0.070 | -0.0441 | Yes | ||
| 67 | CCDC88A | 5807 | 0.067 | -0.0476 | Yes | ||
| 68 | DDB1 | 5865 | 0.066 | -0.0467 | Yes | ||
| 69 | MSH4 | 5956 | 0.063 | -0.0477 | Yes | ||
| 70 | SETMAR | 5962 | 0.063 | -0.0440 | Yes | ||
| 71 | NUP98 | 6087 | 0.060 | -0.0468 | Yes | ||
| 72 | GTF2H1 | 6109 | 0.060 | -0.0440 | Yes | ||
| 73 | DKC1 | 6130 | 0.059 | -0.0411 | Yes | ||
| 74 | MSH6 | 6174 | 0.058 | -0.0395 | Yes | ||
| 75 | TBRG1 | 6319 | 0.055 | -0.0434 | Yes | ||
| 76 | RAD17 | 6346 | 0.054 | -0.0408 | Yes | ||
| 77 | GLI2 | 6380 | 0.053 | -0.0387 | Yes | ||
| 78 | CDC45 | 6427 | 0.052 | -0.0372 | Yes | ||
| 79 | TSN | 6433 | 0.052 | -0.0335 | Yes | ||
| 80 | PIF1 | 6486 | 0.051 | -0.0324 | Yes | ||
| 81 | HUS1 | 6527 | 0.050 | -0.0306 | Yes | ||
| 82 | UVRAG | 6528 | 0.050 | -0.0267 | Yes | ||
| 83 | UBE2V1 | 6727 | 0.045 | -0.0335 | Yes | ||
| 84 | POLI | 6742 | 0.045 | -0.0303 | Yes | ||
| 85 | NASP | 6833 | 0.043 | -0.0313 | Yes | ||
| 86 | MCM3AP | 6835 | 0.043 | -0.0274 | Yes | ||
| 87 | PTGES3 | 7005 | 0.039 | -0.0326 | Yes | ||
| 88 | POLE | 7013 | 0.039 | -0.0290 | Yes | ||
| 89 | VCP | 7136 | 0.036 | -0.0317 | Yes | ||
| 90 | DBF4 | 7213 | 0.035 | -0.0319 | Yes | ||
| 91 | RAD51C | 7251 | 0.034 | -0.0300 | Yes | ||
| 92 | DNASE2 | 7263 | 0.034 | -0.0266 | Yes | ||
| 93 | TGFB1 | 7321 | 0.033 | -0.0258 | Yes | ||
| 94 | NOL8 | 7537 | 0.028 | -0.0335 | Yes | ||
| 95 | TEP1 | 7544 | 0.028 | -0.0299 | Yes | ||
| 96 | WRNIP1 | 7727 | 0.024 | -0.0358 | Yes | ||
| 97 | FANCC | 7749 | 0.024 | -0.0330 | Yes | ||
| 98 | MCM5 | 7761 | 0.024 | -0.0297 | Yes | ||
| 99 | ALKBH1 | 7770 | 0.024 | -0.0262 | Yes | ||
| 100 | KPNA1 | 7844 | 0.022 | -0.0262 | Yes | ||
| 101 | HMGB1 | 7903 | 0.021 | -0.0254 | Yes | ||
| 102 | ERCC8 | 7917 | 0.021 | -0.0221 | Yes | ||
| 103 | SET | 7928 | 0.021 | -0.0187 | Yes | ||
| 104 | RPAIN | 7943 | 0.020 | -0.0155 | Yes | ||
| 105 | SMG6 | 7945 | 0.020 | -0.0116 | Yes | ||
| 106 | ORC4 | 7970 | 0.020 | -0.0090 | Yes | ||
| 107 | KIN | 7980 | 0.020 | -0.0055 | Yes | ||
| 108 | UBE2A | 8073 | 0.018 | -0.0066 | Yes | ||
| 109 | CEBPG | 8171 | 0.016 | -0.0079 | Yes | ||
| 110 | DNMT3A | 8224 | 0.015 | -0.0068 | Yes | ||
| 111 | MSH5 | 8258 | 0.014 | -0.0046 | Yes | ||
| 112 | ERCC3 | 8288 | 0.013 | -0.0022 | Yes | ||
| 113 | TFAM | 8365 | 0.012 | -0.0024 | Yes | ||
| 114 | RAD1 | 8370 | 0.012 | 0.0013 | Yes | ||
| 115 | HELLS | 8405 | 0.011 | 0.0034 | Yes | ||
| 116 | DMAP1 | 8456 | 0.010 | 0.0046 | Yes | ||
| 117 | KAT5 | 8466 | 0.010 | 0.0081 | Yes | ||
| 118 | ABL1 | 8493 | 0.009 | 0.0106 | Yes | ||
| 119 | PMS2 | 8607 | 0.007 | 0.0084 | Yes | ||
| 120 | IGHMBP2 | 8688 | 0.005 | 0.0080 | Yes | ||
| 121 | UBE2V2 | 8715 | 0.005 | 0.0106 | Yes | ||
| 122 | MNAT1 | 8754 | 0.004 | 0.0125 | Yes | ||
| 123 | NAP1L1 | 8779 | 0.004 | 0.0151 | Yes | ||
| 124 | PARP1 | 8845 | 0.002 | 0.0155 | Yes | ||
| 125 | TLK1 | 8868 | 0.002 | 0.0183 | Yes | ||
| 126 | RAD51B | 8953 | 0.000 | 0.0177 | Yes | ||
| 127 | XRCC6 | 8983 | -0.000 | 0.0200 | Yes | ||
| 128 | REC8 | 8996 | -0.001 | 0.0233 | Yes | ||
| 129 | XAB2 | 9003 | -0.001 | 0.0270 | Yes | ||
| 130 | ERCC5 | 9014 | -0.001 | 0.0304 | Yes | ||
| 131 | MMS19 | 9052 | -0.002 | 0.0323 | Yes | ||
| 132 | TNFSF13 | 9130 | -0.004 | 0.0321 | Yes | ||
| 133 | RPA3 | 9158 | -0.004 | 0.0346 | Yes | ||
| 134 | TERF2 | 9203 | -0.005 | 0.0361 | Yes | ||
| 135 | CYCS | 9213 | -0.005 | 0.0396 | Yes | ||
| 136 | SMARCB1 | 9276 | -0.006 | 0.0402 | Yes | ||
| 137 | NBN | 9337 | -0.008 | 0.0408 | Yes | ||
| 138 | XRN2 | 9481 | -0.010 | 0.0370 | Yes | ||
| 139 | RAN | 9514 | -0.011 | 0.0392 | Yes | ||
| 140 | PPT1 | 9515 | -0.011 | 0.0432 | Yes | ||
| 141 | POLD4 | 9627 | -0.014 | 0.0411 | Yes | ||
| 142 | GTPBP4 | 9630 | -0.014 | 0.0449 | Yes | ||
| 143 | PARP3 | 9631 | -0.014 | 0.0489 | Yes | ||
| 144 | TYMP | 9739 | -0.016 | 0.0470 | Yes | ||
| 145 | TLK2 | 9758 | -0.016 | 0.0500 | Yes | ||
| 146 | DNMT3B | 9777 | -0.017 | 0.0530 | Yes | ||
| 147 | REPIN1 | 9781 | -0.017 | 0.0568 | Yes | ||
| 148 | RAD51D | 9895 | -0.019 | 0.0546 | Yes | ||
| 149 | PMS1 | 9977 | -0.020 | 0.0541 | Yes | ||
| 150 | PICK1 | 10017 | -0.021 | 0.0559 | Yes | ||
| 151 | RFC3 | 10089 | -0.022 | 0.0560 | Yes | ||
| 152 | MPG | 10093 | -0.022 | 0.0598 | Yes | ||
| 153 | GATAD2A | 10123 | -0.023 | 0.0622 | Yes | ||
| 154 | CECR2 | 10133 | -0.023 | 0.0657 | Yes | ||
| 155 | POLL | 10140 | -0.023 | 0.0693 | Yes | ||
| 156 | POLG2 | 10162 | -0.023 | 0.0721 | Yes | ||
| 157 | CSNK1D | 10177 | -0.024 | 0.0753 | Yes | ||
| 158 | SUMO1 | 10247 | -0.025 | 0.0755 | Yes | ||
| 159 | POLG | 10274 | -0.025 | 0.0780 | Yes | ||
| 160 | MGMT | 10385 | -0.028 | 0.0760 | Yes | ||
| 161 | DUT | 10387 | -0.028 | 0.0799 | Yes | ||
| 162 | XRCC3 | 10402 | -0.028 | 0.0831 | Yes | ||
| 163 | UNG | 10470 | -0.029 | 0.0834 | Yes | ||
| 164 | CDK2AP1 | 10537 | -0.031 | 0.0837 | Yes | ||
| 165 | TINF2 | 10724 | -0.035 | 0.0776 | Yes | ||
| 166 | AIFM1 | 10743 | -0.035 | 0.0805 | Yes | ||
| 167 | RAD52 | 10747 | -0.035 | 0.0843 | Yes | ||
| 168 | PRIM1 | 10763 | -0.035 | 0.0875 | Yes | ||
| 169 | RUVBL2 | 10866 | -0.038 | 0.0859 | Yes | ||
| 170 | RECQL5 | 10934 | -0.040 | 0.0862 | Yes | ||
| 171 | UBE2B | 10935 | -0.040 | 0.0901 | Yes | ||
| 172 | BNIP3 | 10944 | -0.040 | 0.0937 | Yes | ||
| 173 | TPD52L1 | 10967 | -0.041 | 0.0964 | Yes | ||
| 174 | PNKP | 10982 | -0.041 | 0.0996 | Yes | ||
| 175 | CDK2 | 11000 | -0.041 | 0.1026 | Yes | ||
| 176 | FEN1 | 11034 | -0.042 | 0.1048 | Yes | ||
| 177 | SOD1 | 11052 | -0.043 | 0.1078 | Yes | ||
| 178 | POLB | 11141 | -0.045 | 0.1070 | Yes | ||
| 179 | ERCC2 | 11152 | -0.045 | 0.1104 | Yes | ||
| 180 | SMARCAL1 | 11179 | -0.046 | 0.1129 | Yes | ||
| 181 | UBE2N | 11206 | -0.047 | 0.1155 | Yes | ||
| 182 | IL4 | 11242 | -0.048 | 0.1175 | Yes | ||
| 183 | MCM7 | 11334 | -0.050 | 0.1165 | Yes | ||
| 184 | DFFA | 11355 | -0.050 | 0.1194 | Yes | ||
| 185 | RAD23B | 11359 | -0.050 | 0.1232 | Yes | ||
| 186 | PTMS | 11481 | -0.053 | 0.1205 | Yes | ||
| 187 | CHEK1 | 11554 | -0.054 | 0.1206 | Yes | ||
| 188 | DNMT1 | 11684 | -0.058 | 0.1175 | Yes | ||
| 189 | TIPIN | 11806 | -0.060 | 0.1149 | Yes | ||
| 190 | POLE3 | 11839 | -0.062 | 0.1171 | Yes | ||
| 191 | OGG1 | 11849 | -0.062 | 0.1205 | Yes | ||
| 192 | RNASEH2A | 11905 | -0.063 | 0.1215 | Yes | ||
| 193 | POT1 | 11976 | -0.065 | 0.1216 | Yes | ||
| 194 | ERCC1 | 11992 | -0.065 | 0.1248 | Yes | ||
| 195 | CIB1 | 12043 | -0.066 | 0.1260 | Yes | ||
| 196 | BLM | 12264 | -0.071 | 0.1180 | Yes | ||
| 197 | POLE2 | 12277 | -0.071 | 0.1213 | Yes | ||
| 198 | APTX | 12294 | -0.072 | 0.1244 | Yes | ||
| 199 | POLD2 | 12350 | -0.073 | 0.1253 | Yes | ||
| 200 | CDT1 | 12411 | -0.075 | 0.1260 | Yes | ||
| 201 | ORC5 | 12423 | -0.075 | 0.1294 | Yes | ||
| 202 | SUPV3L1 | 12447 | -0.076 | 0.1321 | Yes | ||
| 203 | NAE1 | 12534 | -0.078 | 0.1314 | Yes | ||
| 204 | ACD | 12542 | -0.078 | 0.1349 | Yes | ||
| 205 | SMUG1 | 12608 | -0.081 | 0.1353 | Yes | ||
| 206 | DFFB | 12640 | -0.082 | 0.1376 | Yes | ||
| 207 | MSH2 | 12769 | -0.085 | 0.1346 | No | ||
| 208 | GMNN | 12895 | -0.089 | 0.1317 | No | ||
| 209 | RAD23A | 13257 | -0.100 | 0.1161 | No | ||
| 210 | APEX1 | 13312 | -0.102 | 0.1171 | No | ||
| 211 | DDB2 | 13427 | -0.106 | 0.1148 | No | ||
| 212 | RAD9A | 13508 | -0.108 | 0.1144 | No | ||
| 213 | NF2 | 13531 | -0.109 | 0.1172 | No | ||
| 214 | EGF | 13596 | -0.111 | 0.1176 | No | ||
| 215 | POLH | 13597 | -0.111 | 0.1216 | No | ||
| 216 | RPA2 | 13810 | -0.120 | 0.1140 | No | ||
| 217 | RFC4 | 13817 | -0.120 | 0.1176 | No | ||
| 218 | MUTYH | 13929 | -0.125 | 0.1156 | No | ||
| 219 | FANCA | 13979 | -0.127 | 0.1168 | No | ||
| 220 | PRIM2 | 13994 | -0.128 | 0.1200 | No | ||
| 221 | TREX2 | 14188 | -0.138 | 0.1135 | No | ||
| 222 | POLD1 | 14247 | -0.141 | 0.1143 | No | ||
| 223 | KCTD13 | 14341 | -0.146 | 0.1132 | No | ||
| 224 | RECQL4 | 14434 | -0.150 | 0.1121 | No | ||
| 225 | FANCG | 14526 | -0.155 | 0.1111 | No | ||
| 226 | BAX | 14600 | -0.158 | 0.1111 | No | ||
| 227 | ASF1A | 14646 | -0.161 | 0.1126 | No | ||
| 228 | CDKN2D | 14651 | -0.161 | 0.1163 | No | ||
| 229 | CDC6 | 14834 | -0.174 | 0.1104 | No | ||
| 230 | PNP | 14864 | -0.176 | 0.1128 | No | ||
| 231 | XRCC6BP1 | 14917 | -0.179 | 0.1139 | No | ||
| 232 | TP53 | 15141 | -0.196 | 0.1057 | No | ||
| 233 | GLI1 | 15289 | -0.208 | 0.1017 | No | ||
| 234 | S100A11 | 15484 | -0.226 | 0.0951 | No | ||
| 235 | NT5M | 15676 | -0.246 | 0.0886 | No | ||
| 236 | ORC1 | 15718 | -0.251 | 0.0903 | No | ||
| 237 | CD40LG | 15950 | -0.282 | 0.0817 | No | ||
| 238 | IGF1 | 16206 | -0.318 | 0.0718 | No | ||
| 239 | NTHL1 | 16239 | -0.325 | 0.0740 | No | ||
| 240 | NHEJ1 | 16551 | -0.388 | 0.0610 | No | ||
| 241 | IGFBP4 | 16585 | -0.396 | 0.0632 | No | ||
| 242 | CCNO | 16694 | -0.425 | 0.0613 | No | ||
| 243 | ADRA1D | 16824 | -0.461 | 0.0582 | No | ||
| 244 | IL7R | 16969 | -0.496 | 0.0543 | No | ||
| 245 | GTF2H4 | 17022 | -0.507 | 0.0554 | No | ||
| 246 | ACHE | 17045 | -0.515 | 0.0582 | No | ||
| 247 | XRCC4 | 17212 | -0.584 | 0.0531 | No | ||
| 248 | FOXL2 | 17284 | -0.620 | 0.0532 | No | ||
| 249 | EREG | 17447 | -0.702 | 0.0483 | No | ||
| 250 | CIDEA | 17546 | -0.764 | 0.0470 | No | ||
| 251 | FOS | 17601 | -0.807 | 0.0480 | No | ||
| 252 | PRKCG | 17625 | -0.827 | 0.0507 | No | ||
| 253 | SYCP1 | 18415 | -2.067 | 0.0117 | No |
